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Level of competition binding experiments done in CHO cell membranes transfected with human CB1 or CB2 receptors discovered affinity values inside the small nanomolar assortment for the two the analyzed compounds AM-2201 and MAM-2201 (Table 1). Similar results have been received analyzing affinity values of The 2 synthetic cannabinoids in mouse tiss
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The course of action was done bilaterally (Over-all rating: 6). Pinna reflex was assessed by touching pavilions (remaining and ideal) with a thin hypodermic needle: 1st the interior pavilions and after that the exterior. This take a look at was repeated 2 times for each side providing a score of 1 if a reflex was present and 0 if it wasn't present
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